Macrolides are a class of antibiotics that are used to treat a variety of bacterial infections. They work by inhibiting the bacteria's ability to produce proteins, which are essential for their growth and replication. Macrolides are effective against a wide range of bacteria, including gram-positive, gram-negative, and atypical bacteria.
Commonly Prescribed Macrolides
Erythromycin
Azithromycin
Clarithromycin
Mechanism of Action
Macrolides exert their antibacterial effects by binding to the bacterial ribosome, the site of protein synthesis. This binding inhibits the translocation step of protein synthesis, leading to the accumulation of incomplete proteins and ultimately bacterial cell death.
Indications
Macrolides are used to treat a variety of infections, including:
The student demonstrates an understanding of how science explains changes in life forms over time, including genetics, heredity, the process of natural selection and biological evolution by showing the relationship between physical characteristics of Alaskan organisms and the environment in which they live.